In the mid-1950s, a scientific consensus arose that cigarettes were the leading cause of lung cancer [...]. The industry responded by launching a massive campaign of denial. Hundreds of scientists were paid to research “alternative causation”, especially maladies caused by constitutional predispositions, viral agents, psychological stress, air pollution, occupational poisons, or anything else that might distract from “the cigarette hypothesis”. From 1964 into the 1970s, cigarette manufacturers paid the American Medical Association (AMA) some US$20 million, in exchange for which the AMA refused to endorse the landmark 1964 Surgeon General's Report indicting cigarettes as a cause of cancer, or the warnings placed on cigarette packs, or the broadcast ban on advertising from 1971. Documents from this period in the industry's archives reveal the industry characterising its chief sponsored research arm—the Council for Tobacco Research—as “a successful defensive operation”.
What is astonishing is how effectively Big Tobacco managed to harness, influence, and sometimes even corrupt large segments of the scientific community. At least 26 Nobel Laureates are known to have taken money from the cigarette industry for research, honoraria, or consulting. In the USA, the industry wielded influence over Congress and the Presidency: Joseph Califano in 1965 urged President Lyndon Johnson to endorse the Surgeon General's Report, for example, but the President refused, explaining that a confrontation with Tobacco could result in [...] losing the Presidency.