Figure 3. Parallel pathways demonstrating the role of Anti-mullerian hormone (AMH) in follicular development in normal (left) versus polycystic (right) ovaries. AMH is produced by the growing follicles and production ceases when the follicles reach a size ≥10 mm. AMH keeps FSH signalling in check. High levels of AMH in PCOS cause increased suppression of FSH signalling and result in (i) arrest in follicular growth, (ii) reduced activation of FSH mediated aromatase activation that contribute to increased androgen levels.
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AMH
